Armour Thyroid Medication Guide: Weight Loss, Dosing, Side Effects & More

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Who needs vitamin B-12 shots and why?
The most obvious benefit of receiving vitamin B shots is treating a vitamin B deficiency and avoiding its associated symptoms. The last increasingly used ingredient for allergies is colostrum. I chose to resign based on my personal beliefs, and I have enough guts to actually be public about it, including using my real name. The median time to onset of rash was 8 days, and the median time to onset of diarrhea was 12 days. I started having stomach aches and felt sick. Creatine also seems to also allow for better pumps during a workout.



Insulin is made by your pancreas, a gland that sits just behind your stomach. It's used for people who have type 2 diabetes that isn't controlled by drugs.

Taking insulin and metformin together aims to combine the benefits of both treatments. Together they give you better control of your blood sugar levels. The metformin may also mean you don't need to take as much insulin. Or is metformin usage for life in terms of controlling blood sugar? A healthy lifestyle including a healthy diet, daily activity, and exercise can help control diabetes and perhaps lessen the need for medications. Your health care provider or diabetes educator is best able to guide your treatment decisions based on your specific circumstances.

Consult them about developing a plan for lifestyle changes that can help you. Can I eat grapefruit every morning? Major clinical trials have not indicated any effects between grapefruit and metformin, even though grapefruit interact with a whole host of other medications. But there are some animal studies that have shown that the combination can lead to complications such as lactic acidosis. Please check with your physician before making any new changes in your diet. For more information on metformin, please see: I am on metformin and my doctor is a holistic devotee so he has me take vitamins and supplements.

Do you have any advice about this? The effectiveness of vitamin and mineral supplements are very patient-specific. Why does my metformin have an odor? I never noticed this before. Only recently within the last month or so, have I noticed this. Metformin is used to help control blood sugar levels in patients with type 2 diabetes.

A recent report in a medical journal indicates that the pills have an odor to them. Pharmacists and other people who take the drug have reported that metformin smells like dead fish, tires, or smelly sweat socks. If you have concerns about the smell or it effects your ability to take the medication, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.

I take mg of metformin twice a day, and there is this horrible fishy smell from the medication, which makes me wonder what's wrong with it?

The article suggests that manufacturers could add a coating to the pill to prevent the odor. If you have concerns about the smell or it affects your ability to take the medication, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action.

Why does my metformin have a fishy smell? Is it still good? I take 1, mg metformin ER morning and at night. I have noticed an odor.

Is it ok to take It? I only smell it if I put my nose to the bottle. Does metformin have a fishy smell, or is it a sign that it's bad and should be thrown out? The metformin I take sometimes when I get it refilled, it smells like fish. Is it still safe to take and effective? A recent report in a medical journal 1 indicates that the pills have an odor to them. Researchers have recently discovered that the popular Type 2 diabetes drug metformin brand names Glumetza, Riomet, Glucophage, Fortamet, and others has a distinctive scent that, for some people, is enough to cause them to stop taking it.

But as the most widely prescribed diabetes drug in the United States, metformin plays an important role in helping people with Type 2 diabetes control their blood glucose levels.

But as the most widely prescribed diabetes drug in the United States, metformin plays an important role in helping people with Type 2 diabetes control their blood glucose levels, and experts have suggested several solutions for dealing with the medicine. Regarding metformin, is it a problem if it smells like fish?

Why does metformin have a bad, fishy odor? Is it safe to continue to take? I have had no problems with the drug besides a slight stomach upset at first. Why does metformin have a bad, fishy odor Does metformin have a suitable relacement that doesn't smell and is as cheap? Some reports indicate that some metformin pills have more odor than others. There are a number of different medications used to treat type 2 diabetes. It works by decreasing the amount of sugar your liver releases and by helping your body to use its own available insulin more efficiently.

Other options include the following: This can lead to low blood sugar levels and weight gain. These drugs can cause upset stomach, gas, and diarrhea. And are other, less odorous options available? Many patients and pharmacists have noticed that metformin glucophage has a fishy odor.

An article in a medical journal states that there appears to be no correlation with the odor of fish associated with metformin and the effectiveness of the medication. It also appears that the fishy odor is seen with the immediate release metformin and not the extended release formulation. If the smell is extremely offensive to you, talk with your physician to see if the extended release tablets would be an appropriate option.

Always store your medications as specified by the storage requirements and do not take expired medications. Click here for additional information provided by Everyday Health regarding diabetes. Why does metformin smell so bad? Does Glucophage smell better? Glucophage is used to help control blood sugar levels in patients with type 2 diabetes. Researchers say the odor varies between generic versions of metformin and seems to be more apparent with the immediate-release form of the drug.

A film-coated, extended-release formulation of metformin may be a good alternative. If you have concerns about the smell or if the odor affects your ability to take the medication, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. My doctor has prescribed another medicine to go with it and it has helped a lot, although I am still craving food in the What is another drug that takes the place of metformin and does not make me crave food or sweets?

It does not usually cause blood sugar levels to go low called hypoglycemia , but if you take other medications for diabetes, drink large amounts of alcohol, exercise heavily, or do not eat enough calories, hypoglycemia may occur.

To raise your blood sugar, eat a quick source of sugar, such as glucose tablets, table sugar, honey, candy, or fruit juice. To help prevent low blood sugar, eat meals on a regular schedule, and do not skip meals. The reverse effect, high blood sugar levels or hyperglycemia, can also occur with metformin and can have the symptom of frequent urination.

It may mean that your dose needs to be adjusted. There are a number of different types of medication used to treat type 2 diabetes. Depending on your blood sugar levels, your doctor may prescribe one or more medications to help control your blood sugar.

Can you please tell me which brand of generic metformin performs the best? I'm sure there is a big difference in absorbability and performance, and I'm sure there is some kind of rating system. It is available by several manufacturers as a generic drug. All generic drugs have the same dosage, intended use, effects, side effects, route of administration, and strength as the brand name drug.

Food and Drug Administration requires that generic drugs be as safe and effective as brand name drugs. Generic versions of a drug often look different from the original brand medication.

This is because trademark laws in the United States do not allow the generic drugs to look exactly like the brand name product. Importantly, the active ingredients are the same in both preparations to ensure that the effect on the body is the same. Concerns are often raised about the quality of generic drugs because they are often substantially less expensive than the brand name drugs. Generic drugs are less expensive because the generic manufacturers do not have to spend substantial money on research, development, and marketing of the drug.

My metformin smells like fish. What does this mean? The metformin drug, why does it smell like fish. It didn't smell like that before. Also like everything you put in your body that's strong is going to come through your body, right! Any alternatives for metformin available?

Metformin Glucophage is unique in the way it works. Other alternatives exist for metformin, but will not work the same way. Unfortunately, it is the only one in this class.

The way that metformin works is that it decreases the amount of sugars glucose that the body absorbs from food.

Other options to metformin include sulfonylureas examples: All of these medications work in different ways and are more appropriate based on individualized needs, the severity of diabetes, side effects and patient response. Also, various therapies are either less expensive or more expensive than metformin.

I have included a few links for more information about diabetes and treatment options. There have been complaints from patients that take metformin Glucophage about an odor that has been described as fishy.

The exact reason for this is unknown but is likely due to the products that are in the tablets. Some patients feel that the smell is only in the immediate release metformin and not the extended release formulation. An article in a medical journal states that there does not seem to be any correlation with the fish smell and how well the medication works. If the smell is extremely unpleasant to you, talk with your physician to determine if changing to the extended release formulation would be an appropriate therapy option for you.

Patients and pharmacists have reported a fishy smell associated with metformin Glucophage. It appears that this is most commonly seen in the immediate release formulation of the medication and not in the extended release tablets.

It is stated in a journal article that the fish smell is not related to the effectiveness of the medication. If the smell is extremely offensive to you, contact your physician to ask if the extended release metformin is an appropriate treatment option for you. It has not been determined what is the exact cause of the odor of Glucophage metformin. Some generic products do not have the smell as much as others do. It all depends on the different binders that the company decides to use.

Binders are found in every tablet and are used to hold the tablet together. While the amount of the medication must remain constant regardless of manufacturer, the binders can vary. If the odor is causing you to not take your medication, you may want to consider trying a different pharmacy to see if they carry a manufacturer with tablets that do not have an odor.

Thank you for submitting your question to Everyday Health. Metformin Glucophage is often described as having an unpleasant, fishy odor but does that mean its spoiled or unsafe? This odor does not affect the effectiveness of the product. Metformin Glucophage is used to help control blood sugar levels in patients with type 2 diabetes. There are also reports of smelly urine in patients who take metformin.

My mom's metformin has a fishy foul odor. The pharmacist and doctor says it's okay. My mom said it never smelled until months ago. Her doctor said to take one instead of two pills.

The pills are mg. Metformin Glucophage has been reported to have a fishy smell by both patients and pharmacists. According to a clinical journal article, there are no correlations between the smell of the medication and how well the medication works. It has also been reported that the smell seems to be most commonly seen with the immediate release metformin and not the extended release metformin tablets. Your mom may want to consult with her physician to determine if the extended release formulation would be an appropriate treatment option for her.

Pain in the muscles and dizziness has also been reported in patients. Please have your mom talk to her physician for further guidance regarding the possible side effects she is experiencing. Dosing of metformin should be done based on her blood sugar levels. Her physician can provide further information about the decision to lower her dosage of the medication. Why does my diabetes drug smell? Is it spoiled or unsafe? One of the diabetes medications that is notorious of having the foul odor is metformin.

Metformin is an oral diabetes medicine that helps control blood sugar levels. There can be a smell with some forms of metformin that is often described as a fishy odor or a locker room odor. This smell is an unpleasant quality of the drug itself and does not affect how it works.

The smell varies among generic products, so it may be more noticeable with some generics than others. It seems to be less noticeable with the extended-release formulations. Most patients are able to tolerate the odor. However, if it is extremely bothersome to you, talk to your doctor or pharmacist.

It may simply be a matter of finding a different generic product and your pharmacist can help you with that. If you find that none of the generics are acceptable to you, consult your doctor to see if an extended-release product may be appropriate for you.

Do not stop taking your medication without talking to your doctor first. Your health care provider is best able to guide your treatment decisions based on your specific circumstances. For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications.

I'm on metformin mg twice a day but right after I take it, I get so sleepy that my brain shuts down. This is not a normal side effect of this medication, according to the prescribing information. This is a symptom that you should report to your physician to be sure that there is no underlying health condition that is causing the issue.

This could be a sign of blood sugar level issues, or a rare side effect known as lactic acidosis. Symptoms of lactic acidosis include: Feeling extremely tired or weak; Muscle pain; Trouble breathing; Abdominal pain or stomach pain ; Feeling cold cold or blue hands and feet ; Dizziness or lightheadedness; A slow or irregular heartbeat; Persistent nausea, vomiting, and abdominal pain; Shortness of breath.

If you are experiencing any of these side effects it should be reported to your physician as soon as possible. I have been told I am a type 2 diabetic and have been taking metformin mg three time a day. Is the medication helping to increase or lower my blood sugar levels? If you have diabetes, your body has problems producing or utilizing insulin. Insulin is a hormone that is produced by your pancreas.

Your body breaks down the food you eat into a form of sugar known as glucose. Insulin is required to convert this glucose into the energy your body needs to grow and perform the activities of daily life.

Diabetes is diagnosed with a simple blood test that measures the level of glucose in your blood, either while you are fasting using the fasting plasma glucose test, or FPG or two hours after drinking a sugary drink using the oral glucose tolerance test, or OGTT. Type 2 diabetes accounts for 90 to 95 percent of all diabetes cases. In type 2 diabetes, the body uses insulin ineffectively, which is called insulin resistance.

Over time, insulin resistance causes a decrease in insulin production, which leads to a build-up of glucose in the blood. When is the best time to take mg of metformin ER, morning or evening? Metformin ER is a prescription medication used to treat type 2 diabetes. It works by decreasing the amount of sugar the liver makes, as well as decreasing the amount of sugar absorbed by the body from the food you eat.

However, as long as the medication is taken at the same time everyday, you can usually choose when you would like that to be based on when you will remember to take it and where it fits into your daily schedule. For more information on metformin ER glucophage XL , click on this link: When should metformin be stopped during pregnancy?

I'm presently on 3 metformin daily. Adverse events have not been observed in animal studies; therefore, metformin is classified as pregnancy category B.

Pharmacokinetic studies suggest that clearance of metformin may be increased during pregnancy and dosing may need adjusted in some women when used during the third trimester. Available information suggests that metformin use during pregnancy may be safe as long as good glycemic control is maintained; however, many studies used metformin during the second or third trimester only. Maternal hyperglycemia can be associated with adverse effects in the fetus, including macrosomia, neonatal hyperglycemia, and hyperbilirubinemia; the risk of congenital malformations is increased when the Hb A1c is above the normal range.

Diabetes can also be associated with adverse effects in the mother. Poorly-treated diabetes may cause end-organ damage that may negatively affect obstetric outcomes. Physiologic glucose levels should be maintained prior to and during pregnancy to decrease the risk of adverse events in the mother and the fetus.

Until additional safety and efficacy data are obtained, the use of oral agents is generally not recommended as routine management of gestational diabetes mellitus GDM or type 2 diabetes mellitus during pregnancy.

Insulin is the drug of choice for the control of diabetes mellitus during pregnancy. For more detailed information, consult with your physician or pharmacist for guidance based on your specific condition and current medications, particularly before taking any action.

I was recently diagnosed with type 2 diabetes and I am taking metformin. My right leg has been killing me at night time early morning. What over the counter medications can I use? I thought maybe an iron defficiency could be the problem. What is a good vitamin supplement. My doctor doesn't want to give me anything but narcotics or other prescription medication. I don't want either. Muscle pain can be a sign of a serious side effect of metformin called lactic acidosis.

Muscle pain, while on metformin, should be evaluated by a medical provider. What will happen if I drink alcohol when taking metformin? Alcohol should be avoided when taking metformin because alcohol lowers the blood sugar and may increase the risk of lactic acidosis.

Lactic acidosis occurs when there is low pH more acidic in the tissues and blood caused by a buildup of lactic acid. This is a rare but deadly condition that is known to be caused by metformin. Your doctor should be able to determine if it is okay for you to drink alcohol and in what quantity while on metformin therapy. Does metformin go through the kidney or the liver? Metformin is eliminated from your body primarily through the kidneys.

It should not be used in patients with kidney disease because it can lead to increased levels of metformin in the body and toxicity. However, metformin should also not be used in patients with liver disease because it increases the risk of a serious side effect called lactic acidosis.

What over-the-counter antidiarrhea medication can I take with metformin? Glucophage metformin is an oral diabetes medication commonly used to control blood sugar levels for Type 2 diabetes.

Common side effects for Glucophage metformin are headache, muscle pain, weakness, nausea, vomiting, diarrhea, gas, and stomach pain. This is not a complete list of the side effects associated with Glucophage metformin. Imodium is an over-the-counter anti-diarrhea medication. There is no drug interaction between Glucophage metformin and Imodium.

Metformin is an oral diabetes medication that helps control blood glucose sugar levels. It is used to treat type 2 diabetes, either alone or in combination with insulin or other medications. Common side effects include headache, weakness, mild nausea, vomiting, diarrhea, gas, and stomach pain. This is not a complete list of side effects that can occur with metformin. Some people have developed a rare but serious, life-threatening condition, called lactic acidosis, while taking metformin.

Seek emergency medical treatment if you experience any symptoms of lactic acidosis including weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting. Kidney problems are not generally caused by metformin itself.

However, metformin should not be used in patients who already have kidney disease because the body uses the kidneys to clear metformin from the blood. If the kidneys cannot do their job properly, high levels of metformin can build up and cause serious side effects. This includes lactic acidosis. So, people with kidney disease are at higher risk for developing lactic acidosis. The risk of lactic acidosis increases when metformin is combined with medications that affect the kidneys, contrast agents for medical tests, or surgery.

All of these increase the risk of kidney problems and lactic acidosis. So, always make sure that all of your health care providers are aware that you take metformin. This is especially important if you have to have an x-ray, CT scan, or surgery. Other risk factors for lactic acidosis include advanced age 80 years and older , alcoholism, and liver disease. If you are concerned about kidney disease, talk to your doctor about your risk factors. Your doctor or health care provider is best able to guide your treatment decisions.

I took metformin ER for years and developed around-the-clock diarrhea for a week. My doctor discontinued the medication and my glucose levels went up. Is there other medication that won't cause those side effects? Glucophage metformin is a medication used for diabetes or to lower blood sugar.

It works by decreasing the amount of glucose that is made by the liver. Glucophage is the only medication in its class, so there is no other medication that works in the same way. There are several other oral medications that treat diabetes but they work in different ways and have different side effects than Glucophage. The most common side effect from Glucophage is diarrhea. Diarrhea can be diminished by taking Glucophage with food. Gastrointestinal side effects decrease with prolonged use of Glucophage so if you recently started on the medication you can expect the side effects will decrease over time.

Discuss any problems you have with your medications with your health care provider. The following link will provide information on other oral diabetes medications.

My pharmacist said that my Glumetza was on back order until the last of September. Should I have my medicine changed? Glumetza metformin is an oral type 2 diabetes medication commonly used to lower blood sugar levels. Glumetza metformin can be used alone or in combination with other diabetes medications to control blood sugar levels. Common side effects of Glumetza metformin include headache, muscle pain, weakness, nausea, vomiting, diarrhea, gas, and abdominal pain.

This is not a complete list of the side effects associated with Glumetza metformin. Glumetza metformin has been recalled and there is no guarantee it will be available in September. Notify your prescribing physician and let them know you are unable to get your medication due to a drug recall. There are other alternative medications available which are very similar to Glumetza metformin including Glucophage metformin , Glucophage XR metformin , Fortamet metformin , and Riomet metformin.

When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your healthcare providers and your pharmacist. If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects.

Metformin Glucophage is classified as a biguanide antidiabetic medication. Metformin is approved for the treatment of type 2 diabetes mellitus. Metformin can be used alone as monotherapy or in combination with other medications such as sulfonylureas or insulin. Metformin works in the body by lowering the amount of glucose that is made by the liver, decreasing the absorption of glucose by the intestines, and improving insulin sensitivity.

Keep in mind these are only possible side effects, they are not guaranteed. Also, this is not all of the side effects reported with metformin. Metformin is one of many different medications available to treat diabetes. Patients can react differently to medications and what may be a good medication for one may not be a good medication for someone else. The decision of what medications to use to treat your medical conditions is best determined by your physician.

When selecting a specific medication to treat a medical condition, there are many variables involved with this decision such as the patient's condition, other medical conditions the patient has, other medications the patient is taking, any drug allergies the patient has, etc. Your health care provider has access to your medical information and is best able to make that decision.

My Metformin smells like fish oil. The report indicates that the odor varies between generic versions of metformin and seems to be more apparent with the immediate-release form of the drug. I've been taking metformin for the past two years. I understand that long-term use of this drug causes kidney problems.

Can you tell me if this is true? There is mention in the medical literature of metformin Glucophage causing lactic acidosis in less than 1 percent of patients taking the medication during clinical trials. The manufacturer lists renal impairment, or kidney problems, as a possible concern with Glucophage. Because metformin is excreted by the kidneys, patients with impaired kidney function should not take the medication. Patients who are dehydrated or have prerenal azotemia a form of kidney failure should also avoid metformin.

Please keep in mind that diabetes itself can cause damage to the kidneys. Discuss your concerns about metformin with your doctor.

My doctor has increased my metformin dosage. Now I have diarrhea, nausea, and leg cramps. Glucophage metformin works by affecting the production of glucose that comes from digestion. If the side effect continues or becomes too bothersome, contact your physician. But don't stop your medication without your physician's approval. Since I've started taking metformin, I'm having breathing problems. Studies have shown that some people have developed a life-threatening condition called lactic acidosis when lactic acid builds up in the blood more quickly than it can be removed while taking metformin.

You may be more likely to develop lactic acidosis if you have congestive heart failure, or if you are older. Talk with your doctor about your symptoms and about your individual risk. Two days after I started taking metformin, my legs started to cramp and burn. I also take Coumadin, Levoxyl, and Dyazide. Could the combination of medications be causing the pain? Close clinical monitoring from a doctor is recommended if you take a diuretic such as Dyazide along with diabetes medications like metformin.

You should notify your doctor if you experience possible signs of lactic acidosis, such as general discomfort, myalgia muscle pain , breathing problems, hyperventilation, slow or irregular heartbeat, sleepiness, or stomach pain. You may need an adjusted dose of metformin. Does metformin cause loose stools and incomplete digestion of food?

If so, what can I do? The most common side effects of metformin are stomach-related problems such as diarrhea, mild nausea, vomiting, gas, and stomach pain. These side effects usually only occur during the first few weeks of taking metformin; they typically improve over time. Work with your doctor to determine the dosage and timing of metformin that's right for you in order to minimize these side effects. For example, you may need to start metformin at the lowest dose and slowly increas it to the recommended dosage.

An extended-release version of metformin, Glucophage, may also help reduce gastrointestinal problems through its slow-release process. Also, diarrhea, nausea, and upset stomach are greatly reduced when metformin is taken with a meal. Lastly, it's important to reduce the amount of fats and sugars you eat while taking metformin. Consuming a diet high in fat or carbohydrates while taking metformin can make stomach problems or diarrhea worse.

People who take metformin with a low-carbohydrate diet find that stomach upset is minimal. If your side effects persist, you can talk to your doctor about trying an over-the-counter antidiarrhea medications such as Imodium or Gas-X. If these side effects last longer than a few weeks and don't go away even if you change your diet, consult with your doctor.

Metformin is a medication prescribed for the treatment of insulin resistance, glucose intolerance and Type 2 Diabetes. Metformin does not cause weight gain. Metformin is recommended to be dosed at dinner. Unfortunately, the side effects of Metformin may require twice a day dosing to decrease the incidence and the severity of side effects.

The side effects for Metformin include abdominal cramping, abdominal pain, nausea, vomiting, gas, and diarrhea. A less common yet serious side effect of Metformin is lactic acidosis. Symptoms of lactic acidosis are shortness of breath, dizziness, lightheadedness, muscle pain, weakness, and a cold sensation.

If you experience any of these symptoms please consult with your physician immediately. Metformin is not recommended in individuals with kidney or liver disease. Alcohol is not recommended when taking metformin.

Any diagnostic procedure such as an x-ray or a cat scan which requires the use of a dye has a serious interaction with Metformin. Therefore, Metformin is recommended to be discontinued 24 to 48 hours prior to the procedure and not restarted for 24 to 48 hours after the procedure to decrease the risk of any interaction between contrast media dye and metformin.

I am 32 years old and was recently placed on metformin mg. The first night I took it I wet my bed. Is this a side effect of metformin?

Glucophage metformin is an oral medication used to treat type 2 diabetes. According to the FDA approved drug information, nocturia excessive nighttime urination is not a side effect of metformin. The most common side effects of metformin are diarrhea, gas, headache, indigestion, nausea, stomach upset, temporary metallic taste, and vomiting.

Nocturia frequently occurs in patients with uncontrolled diabetes. In these cases, excessive glucose sugar in the urine stimulates more urine production. If the wetting episode occurs again, checking your blood glucose immediately will help determine if high blood glucose level is the cause. You should also consult your physician if this happens again. Is one pharmacy's metformin, that is from a different manufacter, the same as another metformin?

Will it bring your sugar down the same way? Glucophage metformin is used for bringing down blood sugar in people who have diabetes. All of the generics are FDA regulated and must have the exact same ingredient that the brand has and in the same quantity. However, inactive ingredients, such as color, flavor, preservatives, etc.

Generic drugs are lower-cost alternatives to more expensive brand-name drugs. They will appear different and have a few other minor differences from the brand-name drugs, but their labeling and directions for use must be virtually the same as that of the brand name product.

Both brand-name and generic drug manufacturing facilities must follow the same standards of good manufacturing practices and meet the U. Food and Drug Administration. I went to my dermatologist about my hair loss and she prescribed metformin. I'm not sure if the benefit would outweigh any risk? Metformin is an oral diabetes medicine that helps control blood glucose sugar levels. Metformin is used to treat type 2 diabetes, either alone or in combination with insulin or other diabetes medications.

These uses have not been approved by the U. Food and Drug Administration and are often referred to as "unlabeled," "off-label," or "unapproved" uses. And it is these inactive ingredients that may cause certain people to respond well or not to these medications due to how they react to these inactive ingredients. In addition these inactive ingredients may alter the breakdown and digestion of which then alters the absorption of thyroid hormone in the body.

Some individuals who take NDT and armour thyroid may experience negative side effects while taking this medication which they may wrongly be attributing to the active thyroid hormone. Instead it may be possible that they would do much better by switching to a different formulation rather than switching back to T4 medication. Using the table below you can see that the NDT form of thyroid hormone with the least amount of ingredients is WP thyroid - though this doesn't necessarily mean that it is the "best".

These changes in inactive ingredients help to explain why some patients react poorly to Armour thyroid with symptoms like headaches, worsening fatigue or rashes - only to find that these symptoms completely resolve upon switching to naturethroid. Again it's not the difference in the concentration of thyroid hormone in each individual medication but most likely a reflection of digestion and absorption.

You can think about methylcellulose as a glue which holds on tight to the thyroid hormone component of the medication and in order for your body to absorb and properly utilize your intestinal tract must separate the methylcellulose from the active thyroid hormone. Unfortunately many patients with hypothyroidism also have gastrointestinal issues including low stomach acid. This may result in decreased absorption of thyroid hormone or cause a "delayed" release of the medication into the blood stream.

In general patients with GI related issues may do better on WP thyroid or Tirosint which both have fewer inactive ingredients and absorption tends to be better. If you aren't familiar with Reverse T3 please read this article. It should come as no surprise then to hear that you don't want high levels of Reverse T3 because it competes for binding with T3 which creates tissue level hypothyroidism or thyroid resistance.

In general, the higher Reverse T3 the more hypothyroid you will feel and the less active thyroid hormone is in your body unless the Reverse T3 is compensatory due to supraphysiologic levels of free T3. High levels of reverse T3 may lead you to experience weight gain, a slower than normal metabolism and other hypothyroid symptoms.

Because T4 has the option to turn into T3 or Reverse T3 we need to concern ourselves with what causes the body to preferentially create more reverse T3.

It turns out that many conditions may be sabotaging your thyroid conversion and the presence of these conditions may be causing your body to turn T4 into reverse T3. As Reverse T3 levels climb your cells will have more difficulty taking up active thyroid hormone. This leads to a situation where you will have the symptoms of hypothyroidism but your lab tests may be "normal". Your temperature will drop, your metabolism will drop and your appetite will increase in an attempt to compensate.

Because high levels of reverse T3 can be caused by different factors, the best way to treat it is to identify the cause and focus on that issue.

If you have high levels of insulin - your focus should be on reversing this condition. If your leptin is too high - then you should undergo therapies designed to reduce leptin resistance.

If you suffer from chronic inflammation then you may need to address whatever issue is causing inflammation in your body. If you can identify and treat these conditions then your body will naturally be able to convert T4 into T3 which is exactly what you want. You can learn more about addressing and treating reverse T3 in this post. Dosing armour thyroid is not much different than using traditional or conventional thyroid medications such as Levothyroxine or Synthroid.

The primary difficulties come when transitioning from an existing thyroid medication over to armour thyroid. If you fall into this category then you need to make sure that you are "converting" your dose correctly as we outlined in the beginning of this post. Many physicians will tend to underdose you on the transition because they aren't familiar with using medications that contain T3.

This underdosing may have the unintended consequence of exacerbating at least temporarily hypothyroid symptoms. Instead make sure you re-evaluate your lab tests and determine if you are on a sufficient dose or if you need a higher dose. Each person will require a unique amount of thyroid hormone but the average dose of armour thyroid is somwhere between grains or mg. Armour thyroid can be dosed in miligrams or in grains and it's important to understand the difference.

If you use the calculation above then 2 grains is equal to mg of armour thyroid or mcg of T4 equivalents if you convert the 18mcg of T3 into T4.

This is helpful because it can help you determine how much armour thyroid to start with and what kind of dose you should be looking to hit. As a general rule of thumb though not always accurate certain patients tend to need higher doses of thyroid hormone. Patients in this category include those with higher metabolic demands those with a higher metabolism , patients who are overweight or who have a higher than average BMI and patients who may be taking medications that block or limit thyroid hormone action.

If you are naive to thyroid medication meaning that you have never tried thyroid medication before then starting off at mg and titrating slowly up every few weeks may also be appropriate. In addition to these general rules there are also other factors that you should consider when using armour: Taking thyroid medication on an empty stomach is usually recommended by physicians and pharmacists because this action may help your body increase absorption.

Thyroid hormone can bind to certain substances which may reduce the dose of thyroid medication that is delivered to your body. Take away from supplements that contain Calcium and Iron but pretty much avoid all supplements if possible. Along the same vein as taking your medication on an empty stomach is to avoid taking your medication with other supplements - especially those that contain calcium or iron.

Calcium and iron are notorious for binding to and preventing the absorption of thyroid hormone, but this can also occur with other supplements. To play it safe I generally recommend that you wait 4 hours after taking any supplement before you also take your thyroid medication. Splitting your dose may help reduce the massive swings in thyroid hormone that occur when you take the entire days worth of thyroid hormone at once.

So if you are taking 2 grains total each day you might consider taking 1 grain in the morning and then another in the afternoon. This can help maintain constant serum levels of thyroid hormone and may be especially helpful for patients who are sensitive to T3. Another strategy that I often recommend is to simply take your thyroid medication at night.

First is that you don't have to worry about taking it on an empty stomach because most people generally don't eat right before bed. And second is that taking your thyroid hormone in the evening may actually improve absorption because the GI tract tends to be slower in the evening. It should be stated that armour thyroid is not a perfect thyroid medication nor will it necessarily work for every person. It's important to remember that armour thyroid comes from an animal and animal tissue is considered "foreign" to your body.

The actual thyroid hormones from the porcine derived thyroid gland are EXACTLY the same as the ones your body produce but, as we stated previously, armour also contains other inactive ingredients that may cause issues when ingested by humans. It's theoretically possible that certain patients taking armour thyroid may experience an "antigenic" reaction. Basically it's possible that your immune system may recognize armour thyroid as "foreign" tissue and react or attempt to destroy it.

Some people believe that taking armour thyroid may cause a "flare up" of existing Hashimoto's disease. While the research is limited in this area I have seen several patients who develop a rapid and excessive increase in thyroid antibodies immediately after starting armour thyroid.

These patients also often experience a worsening in hypothyroid symptoms such as an acute increase in fatigue an increase in weight gain, etc. In my experience this kind of reaction is quite rare but it's worth pointing out for this discussion. If you experience any of these symptoms you should seek help with your physician immediately. This sort of reaction tends to be rare provided you slowly increase your dose over time and monitor your serum thyroid levels as you go.

More common than excessive dosing is insufficient dosing characterized by hypothyroid symptoms: The presence of these symptoms may indicate that your dose is insufficient or not high enough for your body. They also might be a sign that you are having difficulty absorbing or utilizing thyroid hormone after it is absorbed.

If you've been experiencing any of these symptoms then you should have your blood work retested and evaluated. While these symptoms tend to be easy to diagnose there is actually a third reason you might not tolerate armour thyroid and that has to do with sensitivities to inactive fillers and dyes.

These symptoms tend to be unique in the sense that they are NOT caused by the active thyroid hormone but instead caused by the other "stuff" that the medication is formulated with. The good news is that these symptoms often disappear when you switch to "cleaner" medications such as WP thyroid or Tirosint.

At most it will help you lose pounds. If you have hypothyroidism and are more than 20 pounds overweight there is a high chance your weight gain is due to some other hormone imbalance. You won't be able to lose weight unless all 5 of those areas have been addressed and reversed if necessary. Westin Childs is a Doctor of Osteopathic Medicine. He provides well-researched actionable information about hormone-related disorders and formulates supplements to treat these disorders.

His focus is on managing thyroid disorders, weight loss resistance, and other sex hormone imbalances.

You can read more about his own personal journey here. Will taking Armour Thyroid help you lose weight, feel better and have more energy? But will it work for you? Armour also contains less biologically active thyroid hormones such as T1 and T2. Armour thyroid requires less "activation" and is therefore more active when compared to Levothyroxine and Synthroid. The presence of Hormone Imbalances such Leptin Resistance. Side Effects and Symptoms.

Symptoms of excessive Armour thyroid dosing Your dose is too high. Symptoms of insufficient Armour thyroid dosing Your dose is too low. Symptoms of reacting to the fillers or dyes in the medication itself You might want to switch medications. Normal reference ranges for blood vitamin B12 levels differ among laboratories.

Small amounts of animal food, for example after switching from vegan to ovo-laco vegetarian food, may not be enough to treat vitamin B12 deficiency [28].

Vitamin B12 supplements are obtained from bacteria, not animals, so they are vegan, unless gelatin or other animal products are added to them [29]. Toxicity from the overdose of vitamin B12 is not known [1].

Reported harmful effects of vitamin B12 injections: Vitamin B12 in doses larger than Recommended Dietary Allowance 2. Your email address will not be published. The information on this site is for educational purposes only and should not be considered diagnostic or medical advice. Human breast milk and infant formula contain enough vitamin B12 to meet the needs of infants months of age [1,2].

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